JOURNAL CLUB

 

DATE

TOPIC

PRESENTOR

SLIDES

April 6, 2010

 

S Thomas

 

March 30, 2010

mTOR regulates expression of slit diaphragm proteins and cytoskeleton structure in podocytes
Beate Vollenbro¨ker, Britta George, Maria Wolfgart,Moin A. Saleem, Hermann Pavensta¨dt,
and Thomas Weide Am J Physiol Renal Physiol 296: F418–F426, 2009.

M Ghanta

PDF

March 23, 2010

Yadav et al., "Lrp5 Controls Bone Formation by Inhibiting Serotonin Synthesis in the Duodenum," Cell, Nov 2008.

P Canetta

PDF

March 16, 2010

Visel A, Zhu Y, May D, Afzal V, Gong E, Attanasio C, Blow MJ, Cohen JC, Rubin EM, Pennacchio LA. Targeted deletion of the 9p21 non-coding coronary artery disease risk interval in mice. Nature. 2010 Feb 21

S Sanna Cherchi

PDF

March 9, 2010

"Rapamycin Ameliorates PKD Resulting from Conditional Inactivation of Pkd1"

Shillingford JM, Piontek KB, Germino GG, Weimbs T. J Am Soc Nephrol. 2010 Mar;21(3):489-97.

A Valeri

PDF

March 2, 2010

""Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis" Brown EJ, Schlöndorff JS,  et al. Nat Genet. 2010 Jan;42(1):72-6.

F Lugani

 

February 2, 2010

“Urea-induced ROS generation causes insulin resistance in mice with chronic renal failure.” J Clin Invest. 2010;120(1):203–213.

J Crew

 

January 26, 2010

“CD4+ T cells control the differentiation of Gr1+ monocytes into fibrocytes" Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17892-7.

A. Ganda

 

December 15, 2009

Secretin as a neurohypophysial factor regulating body water homeostasis.Chu et al(2009), PNAS 106:37 15961-15966.

G. Williams

 

December 8, 2009

Rickard, Morgan, Tesch et al "Deletion of Mineralocorticoid Receptors From Macrophages Protects Against Deoxycorticosterone/Salt-Induced Cardiac Fibrosis and Increased Blood Pressure.": Hypertension 54: 537-543.

A Bomback

 

November 24, 2009

"Aberrantly glycosylated IgA1 induces mesangial cells to produce platelet-activating factor that mediates nephrin loss in cultured podocytes." J. Clin. Invest. 119(6): 1668-1677 (2009).

A. Gharavi

 

November 17, 2009

De Domenico et al, “Hepcidin-induced internalization of ferroportin requires binding and cooperative interaction with Jak2” PNAS 106(10): 3800-3805.

J. Barasch

 

November 10, 2009

"Depressed expression of Klotho and FGF receptor 1 in hyperplastic parathyroid glands from uremic patients." Kidney Int. 2009 Nov 4.

L. Stern

 

October 13, 2009

“"A loss-of-function nonsynonymous polymorphism in the osmoregulatory TRPV4 gene is associated with human hyponatremia." PNAS  August 18, 2009   vol. 106  no. 33  14034-14039.

J. Radhakrishnan

PPT (PDF)

October 6, 2009

Wnt/Beta Catenin Signaling Promotes Podocyte Dysfunction and AlbuminuriaJASN 20: 1997-2008, 2009

G. Appel

 

September 29, 2009

"The growth factor midkine regulates the renin-angiotensin system in mice" JCI 119(6): 1616-1625 June 2009

J Oliver

 

September 22, 2009

Bicarbonate supplementation slows progression of CKD and improves nutritional status.

J Am Soc Nephrol. 2009 Sep;20(9):2075-84. Epub 2009 Jul 16.  PMID: 19608703

R Seigle

 

September 15, 2009

Molecular clock is involved in predictive circadian adjustment of renal function

PNAS 2009 : 0904890106v1-pnas.0904890106.

Qais Al-Awqati

 

 

 

 

ARCHIVES

DATE

TOPIC

PRESENTED BY

SLIDES

2008, Jun 4

Factor I is required for the development of membranoproliferative glomerulonephritis in factor H-deficient mice.
J Clin Invest. 2008 Feb;118(2):608-18

Barbara Labban

PPT

2008, Jun 24

The Ashwell receptor mitigates the lethal coagulopathy of sepsis. Nat Med. 2008 Jun;14(6):648-55

 

Cheryl Kunis

PPT

2008, Jul 15

TLR4 signaling mediates inflammation and tissue injury in nephrotoxicity.
J Am Soc Nephrol. 2008 May;19(5):923-32.

Martin Nash

PPT

2008, Sep 9

Succinate receptor GPR91 provides a direct link between high glucose levels and renin release in murine and rabbit kidney.
J Clin Invest. 2008 Jul;118(7):2526-34

Qais Al-Awqati

PPT

2008, Sep 16

A tumor necrosis factor-alpha-mediated pathway promoting autosomal dominant polycystic kidney disease.
Nat Med. 2008 Aug;14(8):863-8

Patricia Weng

PPT

2008, Sep 23

The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A.
Nat Med. 2008 Sep;14(9):931-8.

Jai Radhakrishnan

PPT

2008, Sep 30

Deficiency in catechol-O-methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsia.
Nature. 2008 Jun 19;453(7198):1117-21.

Juan Oliver

PPTx

2008, Oct 10

MYH9 is a major-effect risk gene for focal segmental glomerulosclerosis.
Nat Genet. 2008 Oct;40(10):1175-84.

Simone Sanna-Cherchi

PPT

2008, Oct 28

Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant mice.
Nature Medicine 14, 855 - 862 (2008)

Dean Preddie

PPTx

2008. Dec 9

Inhibition of Renal Rho Kinase Attenuates Ischemia Reperfusion-Induced Injury. J  Am Soc Nephrol 19: 2086-2097, 2008

Anthony Valeri

PPT

2009 Mar 10

Combination therapy with AT1 blocker and vitamin D analog markedly ameliorates diabetic nephropathy: blockade of compensatory renin increase.

Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15896-901.

Pietro Canetta

PPT